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Semirational bioengineering of AAV vectors with increased potency and specificity for systemic gene therapy of muscle disorders | Science Advances
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A cross-reactive pH-dependent EGFR antibody with improved tumor selectivity and penetration obtained by structure-guided engineering: Molecular Therapy - Oncolytics
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Nuclear and cytoplasmic huntingtin inclusions exhibit distinct biochemical composition, interactome and ultrastructural properties | Nature Communications
Small-molecule suppression of calpastatin degradation reduces neuropathology in models of Huntington's disease | Nature Communications
In Vivo Pharmacodynamic Method to Assess Complement C5a Receptor Antagonist Efficacy | ACS Pharmacology & Translational Science
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Formation of Neuronal Intranuclear Inclusions Underlies the Neurological Dysfunction in Mice Transgenic for the HD Mutation: Cell
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Cell Type-Specific Transcriptomics Reveals that Mutant Huntingtin Leads to Mitochondrial RNA Release and Neuronal Innate Immune Activation - ScienceDirect
De Novo-Designed Near-Infrared Nanoaggregates for Super-Resolution Monitoring of Lysosomes in Cells, in Whole Organoids, and in Vivo | ACS Nano